Liposomal amphotericin B (AmBisome®) pharmacokinetics: Reaching the skin, review of the literature, and a case series of treated severe disfiguring post kala-azar dermal leishmaniasis

Liposomal amphotericin B (AmBisome®) pharmacokinetics: Reaching the skin, review of the literature, and a case series of treated severe disfiguring post kala-azar dermal leishmaniasis

Post kala-azar dermal leishmaniasis (PKDL) that usually follows successfully treated visceral leishmaniasis (VL) can be severe and disfiguring. Treatment with sodium stibogluconate is prolonged, expensive with colossal cardiorenal toxicities. Early trials with liposomal amphotericin B (AMB) (AmBisom...

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Bibliographic Details
Main Authors: Eltahir Awad Gasim Khalil, B. M. Younis, W. S. E. Seed, M. A. Magzoub, A. M. Elhassan, A. M. Musa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-06-01
Series:Annals of Medical Science and Research
Subjects:
ambisome®
leishmania parasite
parasite wall ergosterol
post kala-azar dermal leishmaniasis
Online Access:https://journals.lww.com/10.4103/amsr.amsr_56_24
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