Neurostimulation device for ameliorating salivary dysfunction: A novel neuromodulatory perspective
Xerostomia, or dry mouth, is a condition characterised by a decrease in salivary flow rate, affecting the quality of life of many individuals. Factors contributing to xerostomia include radiation therapy, pathologies, medications, and age-related loss of salivary gland function. Traditional manageme...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-06-01
|
| Series: | Oral Oncology Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S277290602400219X |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841553786886160384 |
|---|---|
| author | Rajkumar Krishnan Nagarathinam Anbu Elangovan Ramya Ramadoss |
| author_facet | Rajkumar Krishnan Nagarathinam Anbu Elangovan Ramya Ramadoss |
| author_sort | Rajkumar Krishnan |
| collection | DOAJ |
| description | Xerostomia, or dry mouth, is a condition characterised by a decrease in salivary flow rate, affecting the quality of life of many individuals. Factors contributing to xerostomia include radiation therapy, pathologies, medications, and age-related loss of salivary gland function. Traditional management approaches have focused on pharmacological interventions and symptom relief; however, innovative therapies are needed to address the underlying causes of salivary gland dysfunction. Neurostimulation is a rapidly evolving field that holds promise for managing xerostomia by targeting the neural pathways involved in salivary secretion. Studies have shown the efficacy of transcutaneous electrical stimulation in enhancing salivary secretion by selectively activating the nerves innervating the salivary glands. Neurostimulation offers a targeted and personalised approach to treatment, allowing for precise modulation of salivary gland function based on individual patient needs. Neurostimulation devices for xerostomia include the biosonics-SAL salivator system, AdvanTeq 2000, GenNarino, Mediheightec 8000, and the custom extraoral wearable device developed by Rajkumar et al. Neurostimulation is a promising therapeutic approach for managing xerostomia; however, further research is needed to validate the underlying mechanisms and optimise neurostimulation techniques for optimal salivary secretion. |
| format | Article |
| id | doaj-art-f6e5435f00824d9494bb20c03c73c0b9 |
| institution | Kabale University |
| issn | 2772-9060 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral Oncology Reports |
| spelling | doaj-art-f6e5435f00824d9494bb20c03c73c0b92025-01-09T06:15:59ZengElsevierOral Oncology Reports2772-90602024-06-0110100373Neurostimulation device for ameliorating salivary dysfunction: A novel neuromodulatory perspectiveRajkumar Krishnan0Nagarathinam Anbu Elangovan1Ramya Ramadoss2Department of Oral Pathology, SRM Dental College, Ramapuram, Chennai, IndiaDepartment of Oral Pathology, SRM Dental College, Ramapuram, Chennai, India; Corresponding author.Department of Oral Biology, Saveetha Dental College, Chennai, IndiaXerostomia, or dry mouth, is a condition characterised by a decrease in salivary flow rate, affecting the quality of life of many individuals. Factors contributing to xerostomia include radiation therapy, pathologies, medications, and age-related loss of salivary gland function. Traditional management approaches have focused on pharmacological interventions and symptom relief; however, innovative therapies are needed to address the underlying causes of salivary gland dysfunction. Neurostimulation is a rapidly evolving field that holds promise for managing xerostomia by targeting the neural pathways involved in salivary secretion. Studies have shown the efficacy of transcutaneous electrical stimulation in enhancing salivary secretion by selectively activating the nerves innervating the salivary glands. Neurostimulation offers a targeted and personalised approach to treatment, allowing for precise modulation of salivary gland function based on individual patient needs. Neurostimulation devices for xerostomia include the biosonics-SAL salivator system, AdvanTeq 2000, GenNarino, Mediheightec 8000, and the custom extraoral wearable device developed by Rajkumar et al. Neurostimulation is a promising therapeutic approach for managing xerostomia; however, further research is needed to validate the underlying mechanisms and optimise neurostimulation techniques for optimal salivary secretion.http://www.sciencedirect.com/science/article/pii/S277290602400219X |
| spellingShingle | Rajkumar Krishnan Nagarathinam Anbu Elangovan Ramya Ramadoss Neurostimulation device for ameliorating salivary dysfunction: A novel neuromodulatory perspective Oral Oncology Reports |
| title | Neurostimulation device for ameliorating salivary dysfunction: A novel neuromodulatory perspective |
| title_full | Neurostimulation device for ameliorating salivary dysfunction: A novel neuromodulatory perspective |
| title_fullStr | Neurostimulation device for ameliorating salivary dysfunction: A novel neuromodulatory perspective |
| title_full_unstemmed | Neurostimulation device for ameliorating salivary dysfunction: A novel neuromodulatory perspective |
| title_short | Neurostimulation device for ameliorating salivary dysfunction: A novel neuromodulatory perspective |
| title_sort | neurostimulation device for ameliorating salivary dysfunction a novel neuromodulatory perspective |
| url | http://www.sciencedirect.com/science/article/pii/S277290602400219X |
| work_keys_str_mv | AT rajkumarkrishnan neurostimulationdeviceforamelioratingsalivarydysfunctionanovelneuromodulatoryperspective AT nagarathinamanbuelangovan neurostimulationdeviceforamelioratingsalivarydysfunctionanovelneuromodulatoryperspective AT ramyaramadoss neurostimulationdeviceforamelioratingsalivarydysfunctionanovelneuromodulatoryperspective |