Mechanisms of action and therapeutic potential of PCSK9-regulating drugs

Context Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates plasma low-density lipoprotein cholesterol (LDL-C) metabolism and is a key target for cardiovascular therapies. It also plays roles in inflammation, cancer, and metabolic disorders, prompting interest in repurposing PCSK9-target...

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Bibliographic Details
Main Authors: Chenrui Qi, Daming Fan, Lei Wang, Lubo Guo, Huihui Jiang, Lu Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Pharmaceutical Biology
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Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2025.2514021
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