Different Biomechanical Cell Behaviors in an Epithelium Drive Collective Epithelial Cell Extrusion

Different Biomechanical Cell Behaviors in an Epithelium Drive Collective Epithelial Cell Extrusion

Abstract In vertebrates, many organs, such as the kidney and the mammary gland form ductal structures based on the folding of epithelial sheets. The development of these organs relies on coordinated sorting of different cell lineages in both time and space, through mechanisms that remain largely unc...

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Bibliographic Details
Main Authors: Lakshmi Balasubramaniam, Shreyansh Jain, Tien Dang, Emilie Lagoutte, René Marc Mège, Philippe Chavrier, Benoit Ladoux, Carine Rossé
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
cell sorting
collective cell extrusion
dewetting
mechanobiology
Proc Natl Acad Sci USA
Online Access:https://doi.org/10.1002/advs.202401573
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https://doi.org/10.1002/advs.202401573

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