CRISPR-Cas Dynamics in Carbapenem-Resistant and Carbapenem-Susceptible <i>Klebsiella pneumoniae</i> Clinical Isolates from a Croatian Tertiary Hospital

CRISPR-Cas Dynamics in Carbapenem-Resistant and Carbapenem-Susceptible <i>Klebsiella pneumoniae</i> Clinical Isolates from a Croatian Tertiary Hospital

(1) Background: CRISPR-Cas systems provide adaptive immunity against mobile genetic elements (MGEs) carrying antimicrobial resistance (AMR) genes. Carbapenem-resistant (CR) <i>Klebsiella pneumoniae</i> is a major public health concern, and the role of CRISPR-Cas in its resistance is unde...

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Main Authors: Ivana Jurić, Marko Jelić, Manda Markanović, Lucija Kanižaj, Zrinka Bošnjak, Ana Budimir, Tomislav Kuliš, Arjana Tambić-Andrašević, Ivana Ivančić-Baće, Ivana Mareković
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pathogens
Subjects:
<i>Klebsiella pneumoniae</i>
CRISPR-Cas system
CRISPR loci
subtypes I-E and I-E*
carbapenemase genes
carbapenem resistance
Online Access:https://www.mdpi.com/2076-0817/14/6/604
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