Praziquantel plasma concentration and its metabolic ratio suboptimally predict schistosomiasis cure among infected children

Abstract Background In recent years, biomarkers or surrogate endpoints have been shown to be vital in predicting treatment response. In schistosomiasis treatment using praziquantel, it has been suggested that drug level quantified at 4 hours post drug intake is an optimal sampling time for monitorin...

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Bibliographic Details
Main Author: Rajabu Hussein Mnkugwe
Format: Article
Language:English
Published: SpringerOpen 2025-02-01
Series:Bulletin of the National Research Centre
Subjects:
Online Access:https://doi.org/10.1186/s42269-025-01305-7
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