Hypoxia in extravillous trophoblasts links maternal obesity and offspring neurobehavior

Summary: While maternal obesity (MO) is associated with neurobehavioral impairment (NBI) in offspring, the underlying mechanisms remain unknown. The placenta is thought to play a role in fetal programming. To elucidate the association between MO and offspring NBI, we performed single-nucleus RNA-seq...

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Bibliographic Details
Main Authors: Fatima Gunter-Rahman, Shayna Mallett, Frédérique White, Pierre-Étienne Jacques, Ravikiran M. Raju, Marie-France Hivert, Eunjung Alice Lee
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225008971
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