Single-cell transcriptomic profiling reveals diversity in human iNKT cells across hematologic tissues

Single-cell transcriptomic profiling reveals diversity in human iNKT cells across hematologic tissues

Summary: Invariant natural killer T (iNKT) cells are evolutionarily conserved innate lymphocytes important for protection against pathogens, malignancies, and graft-versus-host disease, with potential for universal donor cellular therapies. While mouse studies reveal transcriptionally and functional...

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Main Authors: Reyka G. Jayasinghe, Derek Hollingsworth, Nathan C. Schedler, Emily Landy, Chaiyaporn Boonchalermvichian, Biki Gupta, Hao Yan, Jeanette Baker, Beruh Dejene, Kenneth I. Weinberg, Robert S. Negrin, Melissa Mavers
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725003584
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http://www.sciencedirect.com/science/article/pii/S2211124725003584

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