Development of a Two-Component Nanoparticle Vaccine Displaying an HIV-1 Envelope Glycoprotein that Elicits Tier 2 Neutralising Antibodies

Development of a Two-Component Nanoparticle Vaccine Displaying an HIV-1 Envelope Glycoprotein that Elicits Tier 2 Neutralising Antibodies

Despite treatment and other interventions, an effective prophylactic HIV vaccine is still an essential goal in the control of HIV. Inducing robust and long-lasting antibody responses is one of the main targets of an HIV vaccine. The delivery of HIV envelope glycoproteins (Env) using nanoparticle (NP...

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Bibliographic Details
Main Authors: Kegomoditswe Malebo, Jeremy Woodward, Phindile Ximba, Qiniso Mkhize, Sanele Cingo, Thandeka Moyo-Gwete, Penny L. Moore, Anna-Lise Williamson, Rosamund Chapman
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Vaccines
Subjects:
nanoparticle
mi3
CAP255
DNA
tier 2 neutralising antibodies
human immunodeficiency virus
Online Access:https://www.mdpi.com/2076-393X/12/9/1063
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https://www.mdpi.com/2076-393X/12/9/1063

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