Gut microbiome and metabolome interactions in Crohn’s disease: mechanistic insights into exclusive enteral nutrition-induced remission

Gut microbiome and metabolome interactions in Crohn’s disease: mechanistic insights into exclusive enteral nutrition-induced remission

BackgroundExclusive enteral nutrition (EEN) is a first-line therapeutic approach for inducing remission in Crohn’s disease. However, the underlying mechanisms of its action remain poorly understood. This study aims to investigate the effects of EEN on the gut microbiome and metabolome of CD patients...

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Bibliographic Details
Main Authors: Weiwei Zheng, Quan Zhou, Mengli Xue, Xing Yu, Xue’e Chen, Jintong Chen, Chengdang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Microbiology
Subjects:
Crohn’s disease
exclusive enteral nutrition
gut microbiome
metabolomics
microbiome–metabolome interactions
liquid chromatography–mass spectrometry
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1616122/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1616122/full

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