Investigating shared risk variants and genetic etiology between Alzheimer’s disease and three stress-related psychiatric disorders: a large-scale genome-wide cross-trait analysis

Investigating shared risk variants and genetic etiology between Alzheimer’s disease and three stress-related psychiatric disorders: a large-scale genome-wide cross-trait analysis

IntroductionObservational studies have reported that patients with Alzheimer’s disease (AD) have a greater burden of comorbidities typically associated with stress-related psychiatric disorders. However, the contribution of hereditary factors to this comorbidity remains unclear. We evaluated phenoty...

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Bibliographic Details
Main Authors: Weijia Dang, Tianqi Hao, Ning Li, Hualin Zhang, Ziqi Li, Hongmei Yu, Yalu Wen, Deqiang Zheng, Long Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Aging
Subjects:
Alzheimer’s disease
stress-related psychiatric disorders
genetic correlation
genome-wide cross-trait analysis
shared genetic etiology
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2025.1488528/full
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https://www.frontiersin.org/articles/10.3389/fragi.2025.1488528/full

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