Ambroxol attenuates detrimental effect of LPS-induced glia-mediated neuroinflammation, oxidative stress, and cognitive dysfunction in mice brain

Ambroxol attenuates detrimental effect of LPS-induced glia-mediated neuroinflammation, oxidative stress, and cognitive dysfunction in mice brain

Neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), are multifactorial. Among various factors, lipopolysaccharides (LPSs) from Gram-negative bacteria, such as E. coli, are considered potential causative agents. Despite significant advancements in the field, the...

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Bibliographic Details
Main Authors: Safi Ullah, Tae Ju Park, Jun Sung Park, Abubakar Atiq, Jawad Ali, Min Hwa Kang, Waqar Ali, Kyonghwan Choe, Myeong Ok Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
lipopolysaccharide
neuroinflammation
glial cells
oxidative stress
cognitive
cognitive impairment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1494114/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1494114/full

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