Identification of nitric oxide-mediated necroptosis as the predominant death route in Parkinson’s disease

Identification of nitric oxide-mediated necroptosis as the predominant death route in Parkinson’s disease

Abstract Parkinson's disease (PD) involves multiple forms of neuronal cell death, but the dominant pathway involved in disease progression remains unclear. This study employed RNA sequencing (RNA-seq) of brain tissue to explore gene expression patterns across different stages of PD. Using the S...

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Bibliographic Details
Main Authors: Ting Zhang, Wenjing Rui, Yue Sun, Yunyun Tian, Qiaoyan Li, Qian Zhang, Yanchun Zhao, Zongzhi Liu, Tiepeng Wang
Format: Article
Language:English
Published: Springer 2024-10-01
Series:Molecular Biomedicine
Subjects:
Nitric oxide
Necroptosis
Parkinson's disease
Neurodegenerative disease
Online Access:https://doi.org/10.1186/s43556-024-00213-y
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https://doi.org/10.1186/s43556-024-00213-y

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