Pulmonary features and stage of disease in adult patients with hyper-IgE syndrome: a single-centre clinical study and literature review

Pulmonary features and stage of disease in adult patients with hyper-IgE syndrome: a single-centre clinical study and literature review

Abstract Background The hyper-IgE syndromes (HIES) are a heterogeneous group of inborn errors of immunity-sharing manifestations including increased infection susceptibility, eczema, and raised serum IgE. Pulmonary complications are responsible for high morbidity and mortality rates in patients with...

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Bibliographic Details
Main Authors: Tiange Xie, Na Xu, He Zhao, Yingdong Han, Juan Wu, Hong Di, Min Peng, Ting Zhang, Hongwei Fan, Yun Zhang, Xuejun Zeng
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Hyper-IgE syndromes
STAT3 gene
Primary immunodeficiency
Lung disease
Online Access:https://doi.org/10.1186/s13023-025-03749-6
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https://doi.org/10.1186/s13023-025-03749-6

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