Chromatin endogenous cleavage provides a global view of yeast RNA polymerase II transcription kinetics

Chromatin immunoprecipitation (ChIP-seq) is the most common approach to observe global binding of proteins to DNA in vivo. The occupancy of transcription factors (TFs) from ChIP-seq agrees well with an alternative method, chromatin endogenous cleavage (ChEC-seq2). However, ChIP-seq and ChEC-seq2 rev...

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Main Authors: Jake VanBelzen, Bennet Sakelaris, Donna G Brickner, Nikita Marcou, Hermann Riecke, Niall M Mangan, Jason H Brickner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-11-01
Series:eLife
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Online Access:https://elifesciences.org/articles/100764
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