Variation in the circumsporozoite protein of Plasmodium falciparum: vaccine development implications.

Variation in the circumsporozoite protein of Plasmodium falciparum: vaccine development implications.

The malaria vaccine candidate RTS,S/AS01 is based on immunogenic regions of Plasmodium falciparum circumsporozoite protein (CSP) from the 3D7 reference strain and has shown modest efficacy against clinical disease in African children. It remains unclear what aspect(s) of the immune response elicited...

Full description

Saved in:
Bibliographic Details
Main Authors: Kavita Gandhi, Mahamadou A Thera, Drissa Coulibaly, Karim Traoré, Ando B Guindo, Amed Ouattara, Shannon Takala-Harrison, Andrea A Berry, Ogobara K Doumbo, Christopher V Plowe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0101783
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1371/journal.pone.0101783

Similar Items