Genetically proxied therapeutic effect of antihypertensive drug use, breast cancer, and ovarian cancer’s risk: a drug-target Mendelian randomization study

Genetically proxied therapeutic effect of antihypertensive drug use, breast cancer, and ovarian cancer’s risk: a drug-target Mendelian randomization study

Abstract Background Observational studies have explored the association between antihypertensive drugs and the risk of breast cancer (BC) and ovarian cancer (OC). However, some controversy persists. Objective Our study aims to investigate the causal relationship between genetic proxies for antihyper...

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Bibliographic Details
Main Authors: Chunxiao Dang, Ruohan Wang, Yunzhen Shi, Pengfei Liu, Xiaofeng Wang, Jinxing Liu, Xiao Yu, Dongxu Jin, Qing Ma
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
Antihypertensive drugs
Breast cancer
Ovarian cancer
Mendelian randomization
Drug-Target MR
Online Access:https://doi.org/10.1186/s12885-025-14350-2
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https://doi.org/10.1186/s12885-025-14350-2

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