Force-bearing phagocytic adhesion rings mediate the phagocytosis of surface-bound particles
Abstract Many micro-particles including pathogens strongly adhere to hosts. It remains elusive how macrophages detach these surface-bound particles during phagocytosis. We show that, rather than binding directly to these particles, macrophages form unique β2 integrin-mediated adhesion structures at...
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Main Authors: | Subhankar Kundu, Kaushik Pal, Arghajit Pyne, Xuefeng Wang |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-025-56404-w |
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