Force-bearing phagocytic adhesion rings mediate the phagocytosis of surface-bound particles

Abstract Many micro-particles including pathogens strongly adhere to hosts. It remains elusive how macrophages detach these surface-bound particles during phagocytosis. We show that, rather than binding directly to these particles, macrophages form unique β2 integrin-mediated adhesion structures at...

Full description

Saved in:
Bibliographic Details
Main Authors: Subhankar Kundu, Kaushik Pal, Arghajit Pyne, Xuefeng Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56404-w
Tags: Add Tag
No Tags, Be the first to tag this record!