Predictive modeling to evaluate long-term treatment effectiveness of darvadstrocel in patients with complex perianal fistulas in Crohn’s disease

Predictive modeling to evaluate long-term treatment effectiveness of darvadstrocel in patients with complex perianal fistulas in Crohn’s disease

Abstract Background Current therapies for complex Crohn’s perianal fistulas (CPF) have a limited ability to achieve long-term healing. Darvadstrocel (DVS) is an expanded allogeneic adipose-derived mesenchymal stem cell therapy that has demonstrated efficacy in treating complex CPF in clinical trials...

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Bibliographic Details
Main Authors: Chitra Karki, Gary Hantsbarger, Erika Turkstra, Elisabetta Fenu, Ken Genenz, Inmaculada Gilaberte, Julián Panés
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Gastroenterology
Subjects:
Crohn’s disease
Perianal fistula
Darvadstrocel
Stem cell therapy
Outcome measures
Real-world data
Online Access:https://doi.org/10.1186/s12876-024-03513-3
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