Integrated multi-omics for potential biomarkers and molecular mechanism of persistent inflammatory refractory rheumatoid arthritis

Integrated multi-omics for potential biomarkers and molecular mechanism of persistent inflammatory refractory rheumatoid arthritis

IntroductionPersistent inflammatory refractory rheumatoid arthritis (PIRRA) presents a major clinical challenge, and its underlying molecular mechanisms remain inadequately understood.Methodsathogenesis. Synovial joint tissues were collected from 30 TgTC mice and 30 Friend virus B (FVB) control mice...

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Main Authors: Ping-Heng Zhang, Ya-Nan Bi, Xiao-Feng Zhao, Kang Chen, En-Sheng Chen, Chang-Hong Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
persistent inflammatory refractory rheumatoid arthritis
multi-omics
golgi apparatus
tryptophan metabolism
lipid metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574783/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574783/full

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