A systematic review and embryological perspective of pluripotent stem cell-derived autonomic postganglionic neuron differentiation for human disease modeling

Human autonomic neuronal cell models are emerging as tools for modeling diseases such as cardiac arrhythmias. In this systematic review, we compared 33 articles applying 14 different protocols to generate sympathetic neurons and 3 different procedures to produce parasympathetic neurons. All methods...

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Bibliographic Details
Main Authors: Thomas A Bos, Elizaveta Polyakova, Janine Maria van Gils, Antoine AF de Vries, Marie-José Goumans, Christian Freund, Marco C DeRuiter, Monique RM Jongbloed
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/103728
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