CTCF Represses CIB2 to Balance Proliferation and Differentiation of Goat Myogenic Satellite Cells via Integrin α7β1–PI3K/AKT Axis

CTCF Represses CIB2 to Balance Proliferation and Differentiation of Goat Myogenic Satellite Cells via Integrin α7β1–PI3K/AKT Axis

Skeletal muscle development is a critical economic trait in livestock, governed by myogenic satellite cell regulation. Integrins mediate mechanical anchorage to the ECM and enable ECM–intracellular signaling. <i>CIB2</i>, as an EF-hand-domain protein involved in mechanotransduction, show...

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Bibliographic Details
Main Authors: Changliang Gong, Huihui Song, Zhuohang Hao, Zhengyi Zhang, Nanjian Luo, Xiaochuan Chen
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Series:Cells
Subjects:
<i>CIB2</i>
<i>CTCF</i>
goat
proliferation
breeding strategies
Online Access:https://www.mdpi.com/2073-4409/14/15/1199
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