ELF5 modulates the estrogen receptor cistrome in breast cancer.

ELF5 modulates the estrogen receptor cistrome in breast cancer.

Acquired resistance to endocrine therapy is responsible for half of the therapeutic failures in the treatment of breast cancer. Recent findings have implicated increased expression of the ETS transcription factor ELF5 as a potential modulator of estrogen action and driver of endocrine resistance, an...

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Main Authors: Catherine L Piggin, Daniel L Roden, Andrew M K Law, Mark P Molloy, Christoph Krisp, Alexander Swarbrick, Matthew J Naylor, Maria Kalyuga, Warren Kaplan, Samantha R Oakes, David Gallego-Ortega, Susan J Clark, Jason S Carroll, Nenad Bartonicek, Christopher J Ormandy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1008531&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1008531&type=printable

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