Sex-related differences in genetically determined Alzheimer’s disease

We reviewed the literature on sex differences in genetically determined Alzheimer’s disease (AD), focusing on autosomal dominant AD (ADAD), Down syndrome-associated AD (DSAD), and APOE4 homozygosity, particularly regarding disease penetrance, symptom onset and clinical progression, and trajectories...

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Bibliographic Details
Main Authors: Laura Del Hoyo Soriano, Olivia Wagemann, Alexandre Bejanin, Johannes Levin, Juan Fortea
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Aging Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1522434/full
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