MLH1 Methylation-Based Testing in Peripheral Blood Mononuclear Cells is a Promising Biomarker for Colorectal Cancer Diagnosis and Prognosis

MLH1 Methylation-Based Testing in Peripheral Blood Mononuclear Cells is a Promising Biomarker for Colorectal Cancer Diagnosis and Prognosis

Background: Recent evidence has shown that peripheral blood mononuclear cells (PBMCs) can reflect the epigenetic profile of tissues they interact with, such as malignant cells. The hypermethylation of MLH1 promoter is a well-defined epigenetic alteration in the development of colorectal cancer (CRC)...

Full description

Saved in:
Bibliographic Details
Main Authors: Farzaneh Yousefisadr, Meysam Mosallaei, Shahryar Sadeghi, Hassan Mehrad-Majd, Ali Beheshti Namdar
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2025-04-01
Series:Middle East Journal of Cancer
Subjects:
mlh1
colorectal neoplasms
biomarkers
diagnosis
Online Access:https://mejc.sums.ac.ir/article_50318_686b85f73f169877d7f4515fb555a3a8.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://mejc.sums.ac.ir/article_50318_686b85f73f169877d7f4515fb555a3a8.pdf

Similar Items