Comparison of carbonic anhydrase-IX-targeted trifunctional radioligands between linear- and branched-chain arrangements
BackgroundCarbonic anhydrase-IX (CA-IX) is overexpressed in tumors due to hypoxic conditions and considered an attractive biomarker for tumor-targeting radioligands. The introduction of an albumin binder (ALB) to radioligands can delay their renal clearance, resulting in increased radioactivity deli...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Nuclear Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnume.2025.1585027/full |
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