Study of the Activity of 3-benzyl-5-(4-chloro-arylazo)-4-thioxo-imidazolidin-2-one against Schistosomiasis Mansoni in Mice

Study of the Activity of 3-benzyl-5-(4-chloro-arylazo)-4-thioxo-imidazolidin-2-one against Schistosomiasis Mansoni in Mice

Previous studies conducted with the imidazolidinic derivative 3-benzyl-5-(4-chloro-arylazo)-4-thioxo-imidazolidin-2-one (LPSF-PT05) show outstanding activity against adult Schistosoma mansoni worms in vitro. In the first phase of this study, S. mansoni-infected mice were treated, orally, with 100 mg...

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Main Authors: Andréa Cristina Apolinário da Silva, Juliana Kelle de Andrade Lemoine Neves, João Inácio Irmão, Vláudia Maria Assis Costa, Valdênia Maria Oliveira Souza, Paloma Lys de Medeiros, Eliete Cavalcanti da Silva, Maria do Carmo Alves de Lima, Ivan da Rocha Pitta, Mônica Camelo Pessoa de Azevedo Albuquerque, Suely Lins Galdino
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/520524
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http://dx.doi.org/10.1100/2012/520524

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