Cost-effective solutions for high-throughput enzymatic DNA methylation sequencing.

Cost-effective solutions for high-throughput enzymatic DNA methylation sequencing.

Characterizing DNA methylation patterns is important for addressing key questions in evolutionary biology, development, geroscience, and medical genomics. While costs are decreasing, whole-genome DNA methylation profiling remains prohibitively expensive for most population-scale studies, creating a...

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Main Authors: Amy Longtin, Marina M Watowich, Baptiste Sadoughi, Rachel M Petersen, Sarah F Brosnan, Kenneth Buetow, Qiuyin Cai, Cayo Biobank Research Unit, Michael D Gurven, James P Higham, Heather M Highland, Yi-Ting Huang, Hillard Kaplan, Thomas S Kraft, Yvonne A L Lim, Jirong Long, Amanda D Melin, Michael J Montague, Jamie Roberson, Kee Seong Ng, Michael L Platt, India A Schneider-Crease, Jonathan Stieglitz, Benjamin C Trumble, Vivek V Venkataraman, Ian J Wallace, Jie Wu, Noah Snyder-Mackler, Angela Jones, Alexander G Bick, Amanda J Lea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-05-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011667
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https://doi.org/10.1371/journal.pgen.1011667

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