Utility of serum cytokine testing to differentiate complicated common variable immunodeficiency in resource limited settings

Utility of serum cytokine testing to differentiate complicated common variable immunodeficiency in resource limited settings

Background: Common variable immunodeficiency (CVID) is the most common, symptomatic inborn error of immunity (IEI) worldwide. CVID diagnosis requires lymphocyte subset analysis by flow cytometry to delineate risk for autoimmune and inflammatory (AI) disease, known as complicated CVID. In resource-li...

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Main Authors: Aditi Jogdand, BS, Karen M. Gilbert, PhD, Joseph S. Hong, BS, Andrew J. Pak, BS, Katherine Liu, BA, Uhuru Kamau, MS, Neha V. Khairnar, MS, MBA, Henry C. Ssemaganda, MD, MS, Daniel DiGiacomo, MD, MPH, Sara Barmettler, MD, MPH, Mei-Sing Ong, PhD, Jocelyn R. Farmer, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Common variable immunodeficiency
CVID
autoinflammation
autoimmune and inflammatory
AI
flow cytometry
Online Access:http://www.sciencedirect.com/science/article/pii/S277282932500089X
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