Recoding the Codon Usage of fis Gene of Pasteurella multocida with Rare Codons Reduces Pathogenicity

Recoding the Codon Usage of fis Gene of Pasteurella multocida with Rare Codons Reduces Pathogenicity

Study was undertaken to evaluate gene recoding as an approach for vaccine development. Fis a transcriptional regulatory protein regulates the expression of more than 200 genes in different growth phases and at least 42 genes during exponential growth phase in Pasteurella multocida. We recoded this g...

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Bibliographic Details
Main Authors: Ajeet Kumar, Parthasarathi Behera, Muhammed Kutty, Prabhakar B. Ghorpade, Ajay Kumar, Bhaskar Sharma
Format: Article
Language:English
Published: Journal of Pure and Applied Microbiology 2025-06-01
Series:Journal of Pure and Applied Microbiology
Subjects:
genome recoding
rare codons
pathogenicity
virulence
vaccine
p. multocida
Online Access:https://microbiologyjournal.org/recoding-the-codon-usage-of-fis-gene-of-pasteurella-multocida-with-rare-codons-reduces-pathogenicity/
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https://microbiologyjournal.org/recoding-the-codon-usage-of-fis-gene-of-pasteurella-multocida-with-rare-codons-reduces-pathogenicity/

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