Meta-analyses of adverse effects data derived from randomised controlled trials as compared to observational studies: methodological overview.

<h4>Background</h4>There is considerable debate as to the relative merits of using randomised controlled trial (RCT) data as opposed to observational data in systematic reviews of adverse effects. This meta-analysis of meta-analyses aimed to assess the level of agreement or disagreement...

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Bibliographic Details
Main Authors: Su Golder, Yoon K Loke, Martin Bland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1001026&type=printable
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