CircPRDM5-mediated regulation of miR-433-3p and HDAC6 in Parkinson's disease: a novel neuroprotective axis

Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons, leading to motor and non-motor symptoms. Despite advances in PD research, the molecular mechanisms underlying its pathogenesis remain incompletely understo...

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Bibliographic Details
Main Authors: Kai Wang, Langfeng Zhu, Zhibo Ren
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06602-3
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