Cooperative Interaction of Hyaluronic Acid with Epigallocatechin-3-O-gallate and Xanthohumol in Targeting the NF-κB Signaling Pathway in a Cellular Model of Rheumatoid Arthritis

Cooperative Interaction of Hyaluronic Acid with Epigallocatechin-3-O-gallate and Xanthohumol in Targeting the NF-κB Signaling Pathway in a Cellular Model of Rheumatoid Arthritis

Current intra-articular therapies with hyaluronic acid (HA) provide symptomatic relief in joint diseases, but have limited efficacy in counteracting oxidative stress and inflammation, key drivers of cartilage degradation in rheumatoid arthritis (RA). To address this limitation, the potential of comb...

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Bibliographic Details
Main Authors: Francesco Longo, Alessandro Massaro, Manuela Mauro, Mario Allegra, Vincenzo Arizza, Luisa Tesoriere, Ignazio Restivo
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Antioxidants
Subjects:
hyaluronic acid
xanthohumol
epigallocatechin-3-o-gallate
inflammation
rheumatoid arthritis
Online Access:https://www.mdpi.com/2076-3921/14/6/713
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