Mapping Surface Potential in DNA Aptamer–Neurochemical and Membrane–Ion Interactions on the SOS Substrate Using Terahertz Microscopy

Mapping Surface Potential in DNA Aptamer–Neurochemical and Membrane–Ion Interactions on the SOS Substrate Using Terahertz Microscopy

In this study, we utilized a terahertz chemical microscope (TCM) to map surface potential changes induced by molecular interactions on silicon-on-sapphire (SOS) substrates. By functionalizing the SOS substrate with DNA aptamers and an ion-selective membrane, we successfully detected and visualized a...

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Bibliographic Details
Main Authors: Kosei Morita, Yuta Mitsuda, Sota Yoshida, Toshihiko Kiwa, Jin Wang
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biosensors
Subjects:
terahertz chemical microscope
surface potential
DNA aptamer–neurochemical complexes
membrane–ion interactions
SOS substrate
artificial cerebrospinal fluid
Online Access:https://www.mdpi.com/2079-6374/15/1/46
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https://www.mdpi.com/2079-6374/15/1/46

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