Dasatinib induces apoptosis and autophagy by suppressing the PI3K/Akt/mTOR pathway in bladder cancer cells

Purpose: Bladder cancer is a common genitourinary malignant disease worldwide. Dasatinib is a small molecule inhibitor of Src family kinases. We investigated the anticancer effect and putative molecular mechanisms of dasatinib on T24 and cisplatin-resistant T24R2 human bladder cancer cells. Materia...

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Bibliographic Details
Main Authors: Jin-Nyoung Ho, Seok-Soo Byun, Danhyo Kim, Hoyoung Ryu, Sangchul Lee
Format: Article
Language:English
Published: Korean Urological Association 2024-11-01
Series:Investigative and Clinical Urology
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Online Access:https://www.icurology.org/pdf/10.4111/icu.20240250
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