Revealing the significance of tissue-resident memory T cells in lung adenocarcinoma through bioinformatic analysis and experimental validation

Revealing the significance of tissue-resident memory T cells in lung adenocarcinoma through bioinformatic analysis and experimental validation

PurposeTo investigate the functions of lung TRM cells in the development and treatment of lung adenocarcinoma (LUAD).MethodsR-language bioinformatics analysis was applied to obtain differentially expressed (DE) lung TRM cell-specific genes and a related prognostic signature, which were further valid...

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Bibliographic Details
Main Authors: Zhuoqi Li, Mei Tian, Yuanhui Yang, Yuanyuan Wang, Lu Zhang, Fujing Huang, Xiao Wen, Xiaoshu Yin, Xiaoyan Lin, Yuan Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
TRM cells
LUAD
prognostic signature
immunotherapeutic outcomes
TYMS
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1600863/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1600863/full

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