ALKBH5 activates CEP55 transcription through m6A demethylation in FOXP2 mRNA and expedites cell cycle entry and EMT in ovarian cancer

Abstract Background Centrosomal protein of 55 kDa (CEP55) overexpression has been linked to tumor stage, aggressiveness of the tumor, poor prognosis, and metastasis. This study aims to elucidate the action of CEP55 in ovarian cancer (OC) and the regulation by the alpha-ketoglutarate-dependent dioxyg...

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Bibliographic Details
Main Authors: Junhui Yu, Xing Chen, Xiaoxiao Ding, Kang Lin, Tianxin Zhang, Kai Wang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Biology Direct
Subjects:
Online Access:https://doi.org/10.1186/s13062-024-00551-5
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