Haptoglobin 2-2 genotype is associated with increased risk of cardiovascular disease in patients with rheumatoid arthritis: a matched case-control study

Haptoglobin 2-2 genotype is associated with increased risk of cardiovascular disease in patients with rheumatoid arthritis: a matched case-control study

IntroductionTraditional risk factors do not fully explain the increased risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA). The Haptoglobin (Hp) 2-2 genotype confers a lower anti-oxidant and higher inflammatory effect on the vasculature compared to the non-Hp 2-2 genotyp...

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Bibliographic Details
Main Authors: Chuanhui Xu, Lay Wai Khin, Hui Zhen Tam, Liuh Ling Goh, Ee Tzun Koh, Rinkoo Dalan, Khai Pang Leong
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Medicine
Subjects:
rheumatoid arthritis
cardiovascular disease
Haptoglobin genotypes
inflammation
personalized medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1442858/full
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https://www.frontiersin.org/articles/10.3389/fmed.2024.1442858/full

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