BACE1 inhibitory potential: screening of medicinal plants collected from Nepal high altitude regions

BACE1 inhibitory potential: screening of medicinal plants collected from Nepal high altitude regions

Abstract Fifty-four plant extracts from thirty-two medicinal plants collected in Nepal were evaluated for their inhibitory potential against the enzyme beta-secretase-1 (BACE1), to identify potential therapeutic agents for Alzheimer’s disease (AD). Of the studied extracts, rhizome extract of Rheum a...

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Bibliographic Details
Main Authors: Bishnu Prasad Pandey, Jong Min Oh, Woong-Hee Shin, Abhimat Subedi, Ankita Dahal, Sumit Bhattarai, Hoon Kim
Format: Article
Language:English
Published: SpringerOpen 2024-12-01
Series:Applied Biological Chemistry
Subjects:
Nepal medicinal plants
BACE1 inhibitory potential
Rheum Australe D. Don
HRMS
Molecular docking
Online Access:https://doi.org/10.1186/s13765-024-00974-8
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https://doi.org/10.1186/s13765-024-00974-8

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