H4K20me1 contributes to downregulation of X-linked genes for C. elegans dosage compensation.

H4K20me1 contributes to downregulation of X-linked genes for C. elegans dosage compensation.

The Caenorhabditis elegans dosage compensation complex (DCC) equalizes X-chromosome gene dosage between XO males and XX hermaphrodites by two-fold repression of X-linked gene expression in hermaphrodites. The DCC localizes to the X chromosomes in hermaphrodites but not in males, and some subunits fo...

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Main Authors: Anne Vielle, Jackie Lang, Yan Dong, Sevinc Ercan, Chitra Kotwaliwale, Andreas Rechtsteiner, Alex Appert, Q Brent Chen, Andrea Dose, Thea Egelhofer, Hiroshi Kimura, Przemyslaw Stempor, Abby Dernburg, Jason D Lieb, Susan Strome, Julie Ahringer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002933&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002933&type=printable

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