PGE2 Elevates IL-23 Production in Human Dendritic Cells via a cAMP Dependent Pathway

PGE2 elevates IL-23 production in mouse dendritic cells while inhibits IL-23 production in isolated human monocytes. Whether this differential effect of PGE2 on IL-23 production is cell-type- or species-specific has not been investigated in detail. The present study was designed to investigate the e...

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Bibliographic Details
Main Authors: Quanxing Shi, Zhao Yin, Bei Zhao, Fei Sun, Haisheng Yu, Xiangyun Yin, Liguo Zhang, Shouli Wang
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/984690
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