Intestinal Cells-on-Chip for Permeability Studies

Intestinal Cells-on-Chip for Permeability Studies

Background: To accurately measure permeability of compounds in the intestine, there is a need for preclinical in vitro models that accurately represent the specificity, integrity and complexity of the human small intestinal barrier. Intestine-on-chip systems hold considerable promise as testing plat...

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Bibliographic Details
Main Authors: Marit Keuper-Navis, Hossein Eslami Amirabadi, Joanne Donkers, Markus Walles, Birk Poller, Bo Heming, Lisanne Pieters, Bjorn de Wagenaar, Adam Myszczyszyn, Theo Sinnige, Bart Spee, Rosalinde Masereeuw, Evita van de Steeg
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Micromachines
Subjects:
intestine-on-chip
cell monolayer
in vitro model
intestinal absorption
intestinal barrier
permeability
Online Access:https://www.mdpi.com/2072-666X/15/12/1464
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https://www.mdpi.com/2072-666X/15/12/1464

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