Tacrolimus dosing in liver transplant recipients using phenotypic personalized medicine: A phase 2 randomized clinical trial

Abstract Tacrolimus is the most commonly used immunosuppression drug after solid organ transplantation; however, its dosing is challenging due to substantial inter-individual variability, often resulting in blood levels that deviate from the target therapeutic range. We explored whether a dynamicall...

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Bibliographic Details
Main Authors: Jeffrey Khong, Megan Lee, Curtis Warren, Un Bi Kim, Sergio Duarte, Kenneth A. Andreoni, Sunaina Shrestha, Mark W. Johnson, Narendra R. Battula, Danielle M. McKimmy, Thiago Beduschi, Ji-Hyun Lee, Derek M. Li, Chih-Ming Ho, Ali Zarrinpar
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59739-6
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