The Role of Autoimmune Regulator (AIRE) in Peripheral Tolerance

Autoimmune regulator (AIRE), whose gene mutation is considered to be a causative factor of autoimmune polyglandular syndrome type 1 (APS1), is an important transcriptional regulator. Studies on the role of AIRE in the central immune system have demonstrated that AIRE can eliminate autoreactive T cel...

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Bibliographic Details
Main Authors: Bingjie Zhao, Lu Chang, Haiying Fu, Guangyu Sun, Wei Yang
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2018/3930750
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