Sphingolipid metabolism-related genes as diagnostic markers in pneumonia-induced sepsis: the AUG model

Sphingolipid metabolism-related genes as diagnostic markers in pneumonia-induced sepsis: the AUG model

Abstract Pneumonia-induced sepsis (PIS) is a life-threatening condition with high mortality rates, necessitating the identification of biomarkers and therapeutic targets. Sphingolipid, particularly ceramides, are pivotal in modulating immune responses and determining cell fate. In this study, we ide...

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Main Authors: Jing Wu, Xiaomin Li, Zhihao Chen, Yiting Lin, Qiuyue Long, Mingzheng Jiang, Xiaoyi Hu, Shixu Song, Hongli Ye, Jiwei Li, Fangfang Wu, Jianshi Zheng, Minghui Wang, Zhancheng Gao, Pu Ning, Yali Zheng
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Pneumonia-induced sepsis
Sphingolipid metabolism
Programmed cell death
MIF signaling
Online Access:https://doi.org/10.1038/s41598-025-01150-8
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https://doi.org/10.1038/s41598-025-01150-8

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