Mechanism of Brucea javanica against multiple myeloma via TNF-NF-κB signaling

Mechanism of Brucea javanica against multiple myeloma via TNF-NF-κB signaling

Abstract This study aims to explore the pharmacological mechanism of Brucea javanica (BJ) in treating multiple myeloma (MM) through network pharmacology and validate this mechanism via in vitro experiments. Active pharmaceutical ingredients (APIs) of BJ and their potential targets were identified, a...

Full description

Saved in:
Bibliographic Details
Main Authors: Yuan Wang, Aijia Zhang, Yang Chen, Daoda Qi, Chengyi Peng, Zihao Liang, Jingjing Guo, Yan Gu, Hao Li
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Brucea javanica
Luteolin
Multiple myeloma
TNF/NF-κB signaling pathway
Network pharmacology
Traditional Chinese medicine
Online Access:https://doi.org/10.1038/s41598-025-10271-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-10271-z

Similar Items