Importance of Circulating Leptin and Adiponectin in the Causal Pathways Between Obesity and the Development of Colorectal Cancer in Japanese Men

Background: The mechanistic associations between obesity and risk of colorectal cancer (CRC) remain unclear. Here, using body mass index (BMI) as an obesity indicator, we decomposed the total effects of obesity on the risk of CRC into: (1) direct effects, which are possibly mediated by unmeasured or...

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Bibliographic Details
Main Authors: Masataka Taguri, Aya Kuchiba, Taiki Yamaji, Norie Sawada, Atsushi Goto, Motoki Iwasaki, Shoichiro Tsugane
Format: Article
Language:English
Published: Japan Epidemiological Association 2024-12-01
Series:Journal of Epidemiology
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Online Access:https://www.jstage.jst.go.jp/article/jea/34/12/34_JE20230148/_pdf
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