The signature based on interleukin family and receptors identified IL19 and IL20RA in promoting nephroblastoma progression through STAT3 pathway

The signature based on interleukin family and receptors identified IL19 and IL20RA in promoting nephroblastoma progression through STAT3 pathway

Abstract Wilms tumor (WT) is a common renal malignancy in pediatric patients. Interleukin (receptors) (IL(R)s) play significant roles in tumor biology, however, their specific involvement in WT remains inadequately understood. We employed univariate Cox regression analysis to screen for certain IL(R...

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Bibliographic Details
Main Authors: Chen Ding, Hongjie Gao, Liting Zhang, Zhiyi Lu, Bowen Zhang, Ding Li, Fengyin Sun
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Bioinformatics
Wilms tumor
Interleukin (receptors)
IL20RA
Immune infiltration
Epithelial-mesenchymal transition
Online Access:https://doi.org/10.1038/s41598-025-96094-4
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