Anticodon sequence determines the impact of mistranslating tRNAAla variants

Anticodon sequence determines the impact of mistranslating tRNAAla variants

Transfer RNAs (tRNAs) maintain translation fidelity through accurate charging by their cognate aminoacyl-tRNA synthetase and codon:anticodon base pairing with the mRNA at the ribosome. Mistranslation occurs when an amino acid not specified by the genetic message is incorporated into proteins and has...

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Bibliographic Details
Main Authors: Ecaterina Cozma, Megha Rao, Madison Dusick, Julie Genereaux, Ricard A. Rodriguez-Mias, Judit Villén, Christopher J. Brandl, Matthew D. Berg
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:RNA Biology
Subjects:
Mistranslation
tRNAAla
genetic code
expanded decoding
tRNA biology
Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2023.2257471
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https://www.tandfonline.com/doi/10.1080/15476286.2023.2257471

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